Categorías: CONFERENCIA | MEDICINA

A Survey on Degenerative Diseases of the Central Nervous System

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Richard A. Smith

March 23, 2010 | Universidad Francisco Marroquín | Duración:..

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Slides

Content

Initial credits
Introduction
Lou Gehrig's batting average
- Vitamin E treatment
Course of amyotrophic lateral sclerosis (ALS)
Hemispheric involvement in ALS
Cells in the ventral horn
Scientific advances
Protein mutation
Animal experiments
- Removal of mutant protein from motor neurons
Excitotoxicity experiment
- Translational medicine
- Glutamate transporter
- Ceptriaxone use
Neurotrophic factors
- Neurotrophic subtance use
- Insulin related growth factor
- Growth hormone experiment
- Growth factor intraventricular experiment
VEGF treatment
Emotional liability
- Charles Darwin's publication
- Emotionality in ALS example
- Positive emotional control
- Glutamate inhibition drug
- Liability and depression
- ALS patient improvement
Neuroproteinopathies
ALS protein therapies
- Protein aggregation
Abnormal enzymatic activity
Antisense oligonucleotides
- Therapeutic scientific uncertainty
- Intraventricular delivery of antisense oligos
- Protein effects
- Patient experiment
- Preclinical antisense strategy
ALS research team
ALS experimental evolution
Worlwide ALS projects
Question and answer period
- Multiple sclerosis
  - Importance of vitamin D
- Family markers for ALS
- ALS cure development sites
- Alternative treatments to ALS
- Have you observed SOD mutations in other related diseases?
Final words
Final credits

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About this video

Medical investigations and experimental projects have enabled scientists in many countries to obtain greater and improved data on diseases previously unknown to the medical community; that is the case of amyotrophic lateral sclerosis (ALS). In this conference, Richard A. Smith, a specialist in this topic, shares some of the main characteristics of this medical condition and describes possible treatments, as well. He explains its pathological traits and course in the human body through time. Afterwards, he describes how several trial and research experiments, performed by him in different institutions applying different techniques and approaches, have offered the possibility for more treatments. Smith explains how ALS influences behavior in patients and how this neural discovery has led to the opportunity of designing an efficient treatment that can extend the patients quality of life. Finally, he recommends clinicians to always be aware of signs shown by the patients which might help the diagnosis and treatment.

Richard Smith

Richard Smith

Richard A. Smith is the medical director of the Center for Neurologic Study (CNS), principal researcher at Coordinated Clinical Research, and member of the honorary medical staff at Scripps Memorial Hospital in La Jolla, California. He is also a consultant for Isis Pharmaceutical Corporation and Eli Lily. Dr. Smith has published numerous studies in medical and scientific journals and is the editor of two books, Interferon Treatment of Neurologic Disorders and Handbook of Amyotrophic Lateral Sclerosis. Smith holds a BS from Brandeis University and a MD from University of Miami.

Source: www.cnsonline.org
Last update: 03/25/2010

Credits

A Survey on Degenerative Diseases of the Central Nervous Systems
Richard A. Smith

Business School Building, EN-606
Universidad Francisco Marroquín
Guatemala, March 23, 2010

A New Media - UFM production. Guatemala, May 2010
Camera: Joni Vasquez, Jorge Samayoa; digital editing: Adrián Méndez; index and synopsis: Sergio Bustamante; content reviser: Sofía Díaz; publication: Carlos Petz/Daphne Ortiz

This work is licensed under a Creative Commons 3.0 License
Este trabajo ha sido registrado con una licencia Creative Commons 3.0

Obtenido de "http://newmedia.ufm.edu/gsm/index.php/Rsmithdegenerative"

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