00:00    |    
Initial credits
00:06    |    
Introduction
01:47    |    
History and philosophy of the research performed in Chimaltenango
Interest in maternal, infant, and toddler health
Emphasis on improving perinatal health and maternal-offspring nutrition
Common protocol and metabolic studies
06:37    |    
Zinc research on maternal and infant health
08:43    |    
Environmental factors contributing to low birth weight and stunted growth
Poverty and limited education
Recurrent infections
Natural resources pollution
Malnutrition
11:11    |    
Worldwide causes of death for children under 5 years old
12:21    |    
Nutrition and growth in indigenous population of Western Highlands of Guatemala
13:26    |    
Early infant growth rate
14:19    |    
Undernutrition
Wasting 
Stunting
Example of child wasting in Ethiopia
17:30    |    
Relative risk of mortality according to length score
18:31    |    
Long-term associations of infant/toddler stunting
20:17    |    
Research on zinc and copper absorption 
23:00    |    
Multi-country common protocol study of meat as a first complementary food
26:05    |    
Declining linear growth of children in Chimaltenango
Relationship between length at birth and length at three months of age
28:48    |    
Prediction of early post-natal linear growth failure
30:11    |    
Z-score growth rate
Relationship between length and relative rate of weight gain
32:33    |    
Window of opportunity in infant linear growth
Interventions in the second and third trimester
Preconception interventions
Interventions in the first trimester
39:41    |    
Relationship between length at birth and maternal height
40:34    |    
Importance of preconception care
42:54    |    
Importance of interventions in the first trimester
43:28    |    
Epigenetic hypothesis
Role of epigenome
Effects of dietary changes
47:25    |    
Diagram of the direct effects of maternal nutrition
50:15    |    
Possible nutrient and educational interventions in Chimaltenango
52:53    |    
Regional instability
54:12    |    
Question and answer period
How can environmental interventions change the genome without affecting the DNA? How does malnutrition affect neurocognitive development, is there any relationship between biological and social elements?
Epigenetics evidence
Iron research
What is the relationship between linear growth and weight gain?
01:02:11    |    
Final words
01:03:16    |    
Final credits



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Recent Findings on Pre and Postnatal Growth in Chimaltenango

22 de marzo de 2012   | Vistas: 2 |  

Michael Hambidge shares his research discoveries on infant and maternal health and development, performed in Chimaltenango. He explains the reasons for carrying out this investigation, as well as the motivations and interests that led to such important findings.

He lectures about the worldwide situation on child mortality and underdevelopment, focusing on the different variables that have influenced this health-related situation.

Hambidge tells about the role micronutrients play in an infant’s development, and talks about the importance of prenatal and preconception nutrition. Based on multi-country studies, along with common protocol data, he explains the existing relationship between the height and weight of the children measured. He also comments on the window of opportunity in regards to interventions that can be implemented when a deficit in micronutrients is present, but focuses on the importance of key moments of prevention and intervention in the early stages of preconception and post conception.

Finally, he explains the role of the epigenome concerning the modifications on the genetic material of the cell based on the social, environmental, and genetic conditions of a person.




Michael Hambidge is pediatric gastroenterologist. He is Professor Emeritus of Pediatrics at the Intellectual and Developmental Disabilities Research Center Faculty,…

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